Avamin Melts provides all-natural canker sore prevention by time-releasing bioactive vitamin B12 in the mouth. Vitamin B12, as provided in supplements, is not usable by the cells in your body until it has been processed by the liver. Then, it is spread all throughout your body through your blood. Bioactive B12, on the other hand, is immediately usable by the cells lining your mouth. By saturating these cells with Avamin, you can actually prevent painful canker sores from forming.