Panthethine is the biologically active form of pantothenic acid (Vitamin B5). Clinical studies demonstrate pantethine, but not pantothenic acid, can help some individuals break down fatty acids and cholesterol more effectively.

Pantethine, like that found in Cholestoril, is essential for the breakdown of fat into energy. Clinical studies have shown that supplemental pantethine can help some individuals break down triglycerides and cholesterol more efficiently.