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Trans-Pterostilbene Sirtuin Activator


Jarrow Formulas Trans-Pterostilbene as pTeroPure is 99% pure pterostilbene. Pterostilbene is a methylated natural-occurring form of resveratrol and has better uptake and metabolic stability in the body. Pterostilbene is a calorie restriction mimetic that activates the sirtuin pathway. Emerging science suggests that pterostilbene may exhibit special benefits in brain function and health.

Pterostilbene's Healthy Potential
Berry compound may inhibit breast cancer and heart disease. Blueberries are packed with healthful phytochemicals such as pterostilbene, which has been shown to lower cholesterol in some lab animals. You may not have heard of pterostilbene (pronounced "tero-STILL-bean") yet. But this berry compound's prospects for inhibiting breast cancer, diabetes, and LDL cholesterol in humans may soon make it as well known as other health-enhancing natural substances. Standing to reap benefits from pterostilbene s renown are producers of blueberries and grapes, two fruits known to contain this compound.

The more we study pterostilbene, the more we see its huge potential in the human health field, says chemist Agnes Rimando of ARS s Natural Products Utilization Research Laboratory in Oxford, Mississippi. Her animal studies on the compound have led to several groundbreaking discoveries. Pterostilbene is one of many aromatic hydrocarbons called stilbenes. It s a derivative of resveratrol, a compound found in large quantities in the skins of red grapes. Resveratrol burst on the health scene more than a decade ago, when it was found to have cardiovascular and cancer-fighting benefits.

Studies at the time examined resveratrol s role in an apparent phenomenon in which people in France live long lives despite diets very high in saturated fat and cholesterol. It has been theorized, though not yet proven, that red wine s prevalence in the French diet lowers incidence of cardiovascular disease. Originally isolated from red sandalwood (Pterocarpus santalinus), pterostilbene had already been touted for its fungicidal and antidiabetic properties and showed potential for lowering blood glucose when Rimando started experimenting with it in the early 1990s.

Actually, I isolated pterostilbene from a plant from Thailand back when I was a graduate student at the University of Illinois at Chicago (UIC), says Rimando. At that time, I found it to be toxic to a few cancer cell lines, especiallly breast cancer cells. Later, I had a renewed interest in whether pterostilbene might inhibit cancer when resveratrol was reported to have cancer-preventive activity.

Through experiments using mice, rats, and hamsters, Rimando and collaborators have since helped add chapters to what s known about pterostilbene and what it can do.

About Jarrow Formulas
Jarrow Formulas, which is based in Los Angeles, California, USA, is a formulator and supplier of superior nutritional supplements. The company was founded in 1977 and incorporated in 1988. Today it markets its products in the United States, Mexico, Canada and throughout the world. The owners and officers of the company are: Jarrow L. Rogovin, President; Ben Khowong, CEO/CFO and Peilin Guo, Executive Vice President.

Jarrow Formulas' mission is reflected in its motto 'Superior Nutrition and Formulation".

Jarrow Formulas' complete line of nutritional products includes vitamins, minerals, probiotics, standardized herbal concentrates, amino acids, enzymes and enteral nutrition products. Both retailers and consumers are assured of purity, value and potency when choosing these products.

The company is active in monitoring governmental regulatory affairs, which affect the nutritional industry. It also vigorously promotes the rights of Americans to free access to dietary supplements. Jarrow Formulas funds research studies on important nutritional products such as CoQ10, to ensure that customers receive the full biological value of these products.

Jarrow Formulas' Mission
Jarrow Formulas' goal is to promote optimal health with high quality, effective, affordable and "cutting edge" formulations, which are based on sound scientific research data. The company's professional staff is actively involved in clinical studies and in working with researchers from universities, institutes and other academic environments around the world. Jarrow Formulas strives to provide the best service and technical support to its customers.

* [1] Note: Unless otherwise noted, this product has not been evaluated by the Food and Drug Administration. Our natural products are not intended to diagnose, treat, cure, or prevent any disease.
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