Puffiness occurs when there is excess water in the system resulting from water retention there is a problem with water metabolism in the body. Because the primary organs responsible for water metabolism are the bladder and kidney, Depuff focuses on the kidney s natural ability to flush excess water from the body, thereby reducing the appearance of puffiness.*
*  Note: Unless otherwise noted, products on our web site have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease.