Nutricology QuatreActiv Folate contains Quatrefolic, the glucosamine salt of 5-methyltetrahydrofolate (5-MTHF). Nutricology QuatreActiv Folate patented form of 5-MTHF has demonstrated greater bioavailability than the 5-MTHF calcium salt form. Nutricology QuatreActiv Folate also shows enhanced solubility and stability.
5-MTHF is an essential cofactor in the metabolism of the amino acid metabolite homocysteine. 5-MTHF also must be present in sufficient quantity for normal production of the neurotransmitters serotonin, melatonin, dopamine, epinephrine, and norepinephrine. These functions make 5-MTHF critical for both cardiovascular function and mood support.
Folic acid must be converted to its active forms to be used by the body. This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body's needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.
- A breakthrough in folate supplementation
- The most bioavailable, active form of folate
- An excellent source of folate for pregnant women
- Supports optimal cardiovascular and neurological function
- Made without flowing agents that can inhibit bioavailability
For more than thirty years, NutriCology has been known for the highest quality, most hypoallergenic, and most cutting-edge nutritional supplements available. Physicians and healthcare practitioners around the world depend on NutriCology for their patients' nutritional support. Originating with the ground-breaking oxidant/antioxidant work of Stephen Levine, Ph.D., NutriCology was one of the first to introduce truly hypoallergenic products to the market.
Superior Quality Control
Since 1979, NutriCology has used only the purest raw materials available, and has implemented strict quality control procedures in every stage of production, including inspection of raw materials, manufacturing, packaging, and storing. NutriCology is licensed by the California Department of Health Services, Food and Drug Branch.
Nutricology products are manufactured under the recognized principles of current Good Manufacturing Practice (cGMP), brought into final form by the FDA in June 2007. The GMP standards are applied to a wide variety of procedures associated with the manufacturing of dietary supplements, including receiving, testing, and approval of raw materials, production, and process controls, laboratory testing of labeled and packaged finished product, distribution control and accountability, and shelf life expiration testing to ensure freshness and potency.
For many years they have used the same manufacturers to produce their powder formulas, capsules, tablets, softgels, gels, and liquid products to ensure consistency. All of Nutricology's certified manufacturers meet or exceed cGMP requirements established by the FDA, as well as state and local regulations. In their facility in Alameda, California, highly trained staff bottle, label, and ship finished products. Their newly installed automatic bottling line has multiple built-in quality checks, such as weight verification and metal detection, to ensure all finished packaged products have the pre-determined physical count and are contaminant-free.