Vitamin B6 (pyridoxine HCl), found in conventional supplements, plays a crucial role in numerous life processes. Pyridoxal 5’-phosphate is the metabolically active form of vitamin B6 that has been shown to protect living lipids and proteins against glycation reactions. Aging results in the formation of advanced glycation end products (AGEs) throughout the body. Sugar (glucose) in the blood can react with proteins and lipids in the body, particularly when blood levels are high. This unwanted reaction causes the formation of AGEs, which accumulate with time and contribute to some of the signs of aging.
Life Extension has previously presented information that high-dose carnosine and benfotiamine can be helpful in stopping AGE formation. The latest information shows that pyridoxal 5’-phosphate may also be of significant help in preventing the formation of these aging molecules. By preventing AGE formation and working as a coenzyme in chemical reactions, pyridoxal 5’-phosphate can support healthy nerve, eye, cardiovascular and kidney function. In addition to this standalone product, Life Extension offers pyridoxal 5’-phosphate in two premier formulations: Life Extension Mix and Mitochondrial Energy Optimizer with BioPQQ.